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We measured the levels of the 9 harmful chemicals the World Health Organization recommends reducing in cigarette smoke, which do not include nicotine, and these are reduced on average by 95%

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Add smoke into the mix and youre exacerbating an already serious problem

Another study on human organotypic oral epithelial cultures showed that IQOS, compared to CS, yielded less cytotoxicity (significant after 48 h post-exposure), secretion of proinflammatory mediators, and gene expression perturbations related to apoptosis, necroptosis, senescence, xenobiotic metabolism, and oxidative stress 58