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Chung S, Sperling MR, Biton V, Krauss G, Hebert D, Rudd GD, et al

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Lopez-Castejon G, Brough D (2011) Understanding the mechanism of IL-1 secretion

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The difference in free energy, of electron flow through complexes I and II, accounts for the fact that a pair of electrons originating from NADH and passing to oxygen supports production of 2.5 (more commonly reported as 3) equivalents of ATP, while two electrons from FADH 2 (at complex II) support the production of only 1.5 (more commonly reported as 2) equivalents of ATP