Important considerations include: GLP-1 agonists are generally well-tolerated in people with hypertension They do not typically cause dangerous drops in blood pressure Dehydration from gastrointestinal side effects (nausea, vomiting, diarrhoea) can occasionally affect blood pressure and kidney function, so maintaining adequate fluid intake is important If you take diuretics (water tablets), ACE inhibitors or ARBs for blood pressure, your doctor may monitor you more closely during the initial weeks of GLP-1 therapy Seek medical advice promptly if you experience persistent gastrointestinal symptoms that prevent adequate fluid intake NICE guidance (NG28) supports the use of GLP-1 agonists in people with type 2 diabetes who meet specific criteria, with preference for agents with proven cardiovascular benefits in those with established cardiovascular disease
This transition would involve a bespoke titration schedule and ongoing monitoring to ensure your biological architecture adapts safely to the triple-agonist mechanism
Manufacturers see a fraction of this data, filtered through their own sales tracking systems, specialty pharmacy dispensing reports, and third-party market research that is always lagged and always partial
Take control of your health today with one of Vitalls home blood tests
PMID: 32202086
Initiation rates for ADM GLP-1 RA are about the same in September 2025, relative to June 2025 (+2.0%)
