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Reconstituted solutions should be aliquoted to minimize freeze-thaw cycles

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Conclusion TBI drives changes to cerebral and systemic metabolism that reduce aerobic metabolism of glucose in the brain and compensate by upregulating alternative pathways such as anaerobic glycolysis, lactate fermentation, gluco/ketogenic amino acid metabolism, and lipid metabolism

The increasing incidence of MDR-related infections has led to increased mortality, higher healthcare costs, and the more intensive use of antibiotics [8, 9]

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This becomes particularly important for athletes following rigorous training schedules or participating in multi-day events