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A person with borderline deficiency will certainly reach the ideal level faster than someone with pernicious anemia or severe malabsorption

Escalate only after confirming tolerance and assessing initial response

This makes it particularly relevant in clinical contexts where someone has gut lining compromise alongside systemic inflammation, for example, long-term NSAID use for chronic pain

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Clinical research settings: Some practitioners offer BPC-157 in research or clinical investigation settings where regulatory requirements differ