Lipid-based vesicles are used for agent delivery, because they are able to cross the cell plasmatic membrane and have low cytotoxicity, but there are other more effective delivery systems available, such as nanoparticles, e.g
Patients should be reassured that they have complete flexibility in choosing when to administer their weekly injection relative to meals
However, the medications mechanisms of action can indirectly influence hormonal balance, potentially affecting the menstrual cycle in some individuals
These findings support the further development of this combination as a mechanism-based, dose-efficient therapeutic strategy for neuropathic pain and justify continued evaluation in chronic models across both sexes and translational clinical studies
R01HL168188), the American Heart Association/Harold Amos Medical Faculty Development Program, and the Doris Duke Foundation (Grant #2022051)
1995 Dec:29(12):1263-73. [PMID: 8672832)