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For quantitative synthesis, effect estimates were collected when available, including HRs, 95% CI, and associated p-values

In sICH patients, GLP-1-RAs decreased hydrocephalus (OR 0.37, p = 0.005) and seizures (OR 0.56, p = 0.007) at 6 months, with persistent benefits at 1 year (hydrocephalus, OR 0.38, p = 0.007

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It is a synthetic analog of human GLP-1 with 94% sequence homology, designed to be resistant to dipeptidyl peptidase-4 (DPP-4) degradation, thereby prolonging its half-life to approximately 1 week

doi: 10.1016/j.cmet.2009.10.009