The development of psoriasis is primarily associated with the TNF-/IL-23/IL-17 A axis [192,193,194]
While many people are aware of the unpleasant consequences of this condition, few know that it can be caused by a variety of underlying medications, including using a GLP-1 (glucagon-like peptide-1) agonist drug like Ozempic
As most of these studies only followed patients for a few weeks after stopping the drugs, the team selected the six RCTs (comprising more than 3,200 individuals in total) that followed patients for up to 52 weeks after discontinuation of the weight loss drugs
Tirzepatide, a novel dual glucose-dependent insulinotropic polypeptide and GLP-1 receptor agonist, is currently being developed for the treatment of type 2 diabetes
When two or more doses of the medication are skipped, a person can lose tolerance, increasing the risk of severe side effects once the GLP-1 receptor agonist is resumed
Weight loss accelerates for most researchers at this level