The 2025 NEJM trial comparing tirzepatide directly against semaglutide showed 20.2% versus 13.7% weight loss over the same treatment period
Intriguingly, SP and L-car significantly reduced FOXO1 expression in the POI rat model, together with P53 and caspase-3 downregulation
Consumer framing that treats them as supplements obscures a basic pharmacological reality: compounds that can meaningfully change physiology in a beneficial direction can also change it in an unintended one, and dose, timing, and duration determine which
A 2020 systematic review and meta-analysis published in Clinical Nutrition ESPEN (Asbaghi et al., 12 randomized controlled trials) reported oral berberine supplementation produced a statistically significant weighted mean reduction of 2.07kg in body weight, 0.47 kg/m in BMI, and 1.08cm in waist circumference versus placebo
In this blog, well cover how SIBO develops and break down the seven most important root causes of SIBO, why they matter, and what you can do to prevent SIBO relapse
Shake Shack on GLP-1 comes down to one decision: lettuce wrap or bun