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Valverde, Y., Benson, B., Gupta, M

Statements Author contributions YL: Writing original draft, Conceptualization, Visualization

In obese patients, acipimox can inhibit adipose tissue lipolysis by activating protein upregulated in macrophage by INF- (PUMA-G) (also known as the hydroxycarboxylic acid receptor 2 [HCA2] and GPR109a) receptors

In the FA-AKI model, FA-induced ferroptosis exacerbated renal injury by triggering inflammation to induce other types of cell death, consistent with the increase in the expression of TWEAK and Fn14 in renal tubular epithelial cells in the AKI context [164,165,166]

Synergistic Recovery Effects: Together, these peptides enhance cell survival, vascular growth, and tissue regeneration in a wide range of injury models

Skye SM, Zhu W, Romano KA, Guo CJ, Wang Z, Jia X, Kirsop J, Haag B, Lang JM, DiDonato JA, et al