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Preclinical studies report higher mitochondrial DNA copy numbers and elevated respiratory enzyme levels in muscle tissue, correlating with increased VOmax and reduced fatigue in rodent exercise tests

Furin plays a major role in oocyte development beyond the early secondary follicle stage and any virus-mediated loss of its proteolytic activity could lead to follicular dysplasia and female infertility 354

In animals generally, Rho-family proteins regulate the actin cytoskeleton 28

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39,40,41,42 Similarly, patients with a history of drug or alcohol abuse were excluded by 61% of trials