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Referral criteria for specialist evaluation need clarification and standardization

An important caveat for testing human mAbs in animal models is that human antibody Fc regions may not interact with animal FcRs in the same way as human FcRs 88

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It has a good safety profile, well-tolerated in elderly patients and in patients with co-morbid conditions including risks of cardiovascular event, renal or hepatic insufficiency

2 Given the discomfort and potential complications associated with these sores, effective treatment options are continually being explored

(C) Quantification of oxygen consumption rate (OCR) to assess basal respiration, ATP-linked respiration, maximal respiration, and spare respiratory capacity in TD-N, ASD-N, and ASD-DM NPCs