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The metabolite analysis demonstrated that Nrf2 strongly promotes purine nucleotide synthesis, resulting in the increased production of purine nucleotides

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Clinical research on NAD+ therapy has primarily used intravenous infusions at high doses (5001,000 mg) for applications such as addiction treatment and acute metabolic support [2] [9]

By ligating the arterial supply of the target segment prior to ICG injection, the intersegmental plane is much more easily identified, theoretically reducing the risk of a prolonged postoperative air leak [45]

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