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The heterogeneity in the TME enables it to exhibit various tumour-promoting functions such as immune evasion, cell survival, physical barriers, etc., ultimately leading to the development of multidrug resistance in tumour cells [66]
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In particular, reduced glutathione , often referred to in its fully active form, is the one doing all the heavy lifting
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doi: 10.1097/OGX.0000000000000718
C.ChichlowskiM.BergB
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