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2018;172:40922.e421

Food addiction is the single biggest predictor of weight regain after GLP-1 discontinuation

Sargent BJ, Moore NA

Randomization Coverslips were randomly allocated for TNF-alpha/dAb and MCP-1/dAb samples of different concentrations

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Interestingly, one of the most prominent GLP-1R-cholesterol binding sites identified here lies within the functionally important TM5-TM6 region required for G protein signal transduction, indicating the potential impact of cholesterol binding on GLP-1R activation and downstream signalling