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The idea is to inject as close to the target tissue as possible

For starters, weight loss medication is shown to cause side effects for an overwhelming majority of patients

Tsipas S, Khan T, Loustalot F, Myftari K, Wozniak G

Espinosa-DiezCMiguelVMennerichDKietzmannTSnchez-PrezPCadenasSet al

For instance, in November 2023, results from the SELECT trial published in the New England Journal of Medicine showed that once-weekly semaglutide 2.4 mg reduced the risk of major adverse cardiovascular events by 20% in adults with overweight or obesity and established cardiovascular disease without diabetes, highlighting the expanding role of long-acting GLP-1 analogues beyond glycemic control into cardiovascular risk reduction

Acetaldehyde is metabolized by acetaldehyde dehydrogenase (ALDH genes) into acetic acid, which is non-toxic