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The ratio of GSH to GSSG decreases under stress conditions

Alpha-tocopherol derivatives, such as acetate in alpha-tocopherol acetate, are cleaved prior to absorption in the small intestine by esterases, meaning that alpha-tocopherol is absorbed, not the alpha-tocopherol derivative

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Ferroptosis inhibitor protein 1 (FSP1) is an effective antiferroptosis factor and a coenzyme Q (CoQ) oxidoreductase ( 2 ), which effectively curbs the production of lipid free radicals