In metabolic conditions such as diabetes, prolonged hyperglycemia can damage small nerve fibers through multiple pathways including oxidative stress, accumulation of advanced glycation end products, and microvascular insufficiency affecting nerve blood supply
The trial was designed to evaluate the effect in this population, over a period of up to five years, of a onceweekly subcutaneously administered dose of 2.4 mg semaglutide (Wegovy) on cardiovascular outcomes compared to placebo
The cost of Semaglutide varies depending on the length of the program
"There's a variety of factors in play there
Generic semaglutide medications could reduce Canadian drug plan costs by 65% once Health Canada approves competing versions of the active ingredient found in Ozempic and Wegovy
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