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In particular, these organelles are involved in the regulation of Ca 2+ homeostasis, different mechanisms of programmed cell death, autophagy, and reactive oxygen and nitrogen species (ROS and RNS) production

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These free radicals are natural byproducts of cellular metabolism, but when they accumulate, they cause severe oxidative stress, damaging lipids, proteins, and DNA

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Overall structure of oxidized OsDHAR Initially, DHA-bound OsDHAR structural determination was attempted to examine the DHA binding site and the structural differences compared to the apo form