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Joint discomfort associated with B12 supplementation is uncommon and not listed amongst the recognised adverse effects in the Summary of Product Characteristics (SmPC) for licensed B12 preparations or in the British National Formulary (BNF)
(PubMed) Hutchinson J, Lentjes MA, Greenwood DC, et al
For example, a study published in the American Journal of Clinical Nutrition found that B12 supplements reduced homocysteine levels and improved heart health in older adults
the surplus is excreted
GHK-Cu is an add-on , not a replacement for minoxidil and finasteride
Adding oral B12, sublingual B12, or additional B12 injections poses no risk
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