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Given the important roles of IGF-IR in tumor progression, inhibition of IGF-IR activity has been proposed as a therapeutic strategy for solid tumors and hematologic malignancies [20]

AT 2 receptors were reported to be upregulated and to contribute to Ang II-induced vasodilation in resistance arteries of hypertensive type 2 diabetes patients treated with AT 1 receptor blockers

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Glutathione Peroxidase / STransferase Assays Evaluate enzyme activity and inhibition in models of HO metabolism, organic peroxide reduction, and phase II detoxification of electrophiles