[1] When ovarian production declines after natural menopause, bilateral oophorectomy, gonadotoxic chemotherapy, or primary ovarian insufficiency, compounded estradiol capsules prepared under section 503A enable clinicians to potentially restore physiologic hormone concentrations using patient-specific doses and excipient profiles that may differ from commercial tablets
The suppression of antioxidant proteins, glutathione synthesis enzymes, and NADPH-producing enzymes would lead to ROS accumulation in cancer cells and subsequent oxidative damage to various intracellular components, thus compromising the cell viability
Roden M
"Who should get it and who shouldn't is an argument that really is just based in speculation," Dr Deed said
therefore, consult your doctor before taking it
If you take oral contraception, discuss with your prescriber whether alternative contraceptive methods might be advisable during the first few months of treatment