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[DOI] [PubMed] [Google Scholar] 54.Gibson B.A., Kraus W.L
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In physical dependence assay (isoniazid challenge assessed at 6, 14, 42 and 72 h after conditioning medication), when compared to diazepam non-conditioned healthy mice, in diazepam conditioned mice residual anticonvulsive activity was not present already at the earliest post-conditioning interval (i.e., not different latency to isoniazid-convulsions), whereas shorter preconvulsive latencies (as physical dependence/withdrawal hallmark) were noted in diazepam conditioned mice following isoniazid challenge at 42 h and at 72 h after end of conditioning treatment
Neurosurgery: Advancing Brain and Spine Health By Bob Berendsen February 5, 2025 Neurosurgery is a specialized field of medicine focused on the diagnosis and treatment of disorders affecting the spinal cord, nerves, and peripheral nervous system