FDA Adds Pulmonary Aspiration Warning to GLP-1 Label The FDA has recently updated the labels for all glucagon-like peptide-1 (GLP-1) receptor agonists, a class of medications used for weight loss and diabetes management, with a new safety warning
Particularly, when a high dose (5.4 mg/kg) of LY3502970 was given, the insulin secretion was comparable to that induced by exenatide, and an anorexigenic effect was achieved with just 0.05 mg/kg of LY3502970
Studies show additive increases in circulating GH and IGF-1 levels while preserving natural feedback loops
Weigel MT, Krmer J, Schem C, Wenners A, Alkatout I, Jonat W, Maass N, Mundhenke C (2012) Differential expression of MMP-2, MMP-9 and PCNA in endometriosis and endometrial carcinoma
For people who are overweight or living with obesity and an autoimmune disease, this study offers a hopeful signal that medications already in use today may be beneficial in reducing their risk of cardiovascular disease. More information The Mayo Clinic has more on GLP-1 drug benefits
The prevalence of dyslipidemia in patients on hemodialysis: A cross-sectional study from Syria