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Severity of B12 deficiency : If a confirmed B12 deficiency is present, some doctors will give daily injections to correct the deficiency before switching to a more infrequent maintenance dose

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The therapy is expected to require monthly or less frequent single-injection dosing, making it the first obesity treatment with a longer dosing schedule shown to induce safe and effective weight loss in a Phase II study

Advocates claim that they feel better as a result of regular injections, stating improvements to energy levels, weight, sleep, mood and hair loss

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B-12 injections bypass the digestive system entirely