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Additionally, the cyclic trisulfide structure of LASSS, as opposed to the linear trisulfides such as GSSSG and cysteine trisulfide (Cys-SSS-Cys), could guarantee the unique reactivity of LASSS (see again Figure 1a for chemical structures)

21 Research shows that during high-intensity or multi-stressor field training, Glutathione levels rise as the body adapts to physical stress, while oxidative stress markers decrease, evidence of how the Glutathione system strengthens with consistent activity

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Journal of Physiology-Paris , 87(5), 313327