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12,36 In the muffling process, zinc transporters regulate cellular zinc by importing, distributing, exporting, and providing zinc for zinc-dependent proteins

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Research has shown that AOD-9604 increases lipolytic activity and reduces body weight gain beyond control groups, indicating effects beyond standard caloric management

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Cu co-treatment increased the cellular Zn levels of HT-29 and THP-1 cells but not of HepG2 cells

Therefore, compound 8u may be a potentially effective xanthine oxidase inhibitor for the treatment of hyperuricaemia with low toxicity (Zhang et al., 2019)