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On the neural level, the presence of nicotine and caffeine increase the production of acetylcholine, which in turn increases activation between acetylcholine and the nicotinic 7 receptors

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GEE fits marginal generalised linear models by focusing on models for the mean of the correlated observations within clusters (without fully specifying the joint distribution of the observations) and is particularly suited to analysing clustered data, such as longitudinal data and repeated measures [60]

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Reproductive Health Issues: Complications in pregnancy, reduced fertility, and risks to newborn health