glp 1 gut microbiome Crosstalk between GLP-1 and the microbiome/metabolites Gut microbiome depletion abolishes postprandial

Tirzepatide (Mounjaro, Zepbound) operates through dual mechanisms, targeting both GLP-1 and GIP receptors for enhanced insulin and glucagon regulation

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This is important because there is a high burden of CVD among people with diabetes, and, with ageing of the population, stroke in particular is becoming more frequent among people with type 2 diabetes [20]

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