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2013;1:e52715

The dual role of HSPs depends on stress intensity and duration: Under mild-to-moderate heat stress, HSP70/HSP27 act as protective chaperonespromoting protein folding, inhibiting caspase activation, and reducing apoptosis in mouse models

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When used in skin whitening products, it helps to reduce melanin production, which is responsible for darkening the skin

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This is consistent with other studies that BSO treatment does not considerably alter cell cycle kinetics [58,59]