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Retrieved August 31, 2013

Tobacco smoking reduces p53, a tumor suppressor gene that is considered the genome guardian. Suppression of T-cell responses by Nicotine and tar is associated with decreased surveillance for tumor cells] reported that heavy smokers accumulate excess iron in hepatocytes which induces fibrosis and favors the development of HCC

Avoidance of general anaesthesia should be considered to reduce the risk of aspiration in high risk situations

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Scientific References Non-alcoholic fatty liver disease (NAFLD): assessment and management (NG49)