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You may notice: Nausea, often when starting or increasing the dose A reduced appetite, which supports weight loss Mild stomach discomfort, constipation, or diarrhea Temporary fatigue during early treatment Eating smaller meals, avoiding high-fat foods, and staying hydrated help minimize these effects

As with other GLP-1 analogs, gastrointestinal (GI) events are the most commonly reported adverse effects with semaglutide

Combining GLP-1 receptor agonists with structured lifestyle changes, especially increased protein intake and strength training, can mitigate muscle loss and enhance overall outcomes

Never freeze semaglutide, and keep it within the recommended temperature range

Obesity increases the risk of acute pancreatitis through the following ways

Making the decision: which side effect profile fits your situation After reviewing all this data, the question remains