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Melanomas metastasize either by direct dissemination, by the lymphatic or the haematogenous route [2]
27 Budantseva, L.S
It is constantly exposed to a variety of physical and chemical influences and is therefore most directly affected by ROS, which are produced when skin is exposed to visible light or ultraviolet rays (10)
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It modulates their activation, metabolism, and cytokine release
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