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GLP-1s support weight loss by: Delaying gastric emptying, which helps you feel fuller for longer after meals Regulating blood sugar, which can support steady energy and fewer cravings Reducing appetite and food noise by acting on hunger-regulating areas of the brain While Ozempic, Wegovy, Foundayo, and Zepbound all fall under the GLP-1 umbrella, Zepbound is unique in that it also targets another hormone called GIP (glucose-dependent insulinotropic polypeptide)
[1] [3] In the SURMOUNT-1 trial, adults with obesity or overweight without diabetes experienced dose-dependent weight loss, with higher doses achieving approximately 15-20% weight reduction over 72 weeks
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Once absorbed, it converts enzymatically, first to retinaldehyde, then to retinoic acid, which binds nuclear retinoic acid receptors (RARs) and drives cell-level changes