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The stereochemistry at the -carbon is often a key determinant of pharmacological activity, with ( S )-enantiomers being more potent

Leno cited a study last year by the Centers for Disease Control and Prevention that found the use of e-cigarettes by high school students tripled from 2013 to 2014

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Under the ISO smoking regime, the yields of some toxicants were below the analysis reporting limit, but other than this there was a good deal of consistency in the directional changes across the three smoking regimes