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Smoking has long been proven to negatively affect people's overall health in multiple ways

Similar to health-promoting features, models identified J-shaped associations for self-harm hospitalisations and C-shaped associations for substance problems and health-constraining domains of the HLI, showing a negative association of the outcome with less busy environments (protective effect of poorer access to health-constraining domains)

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[23] analyzed wheezing symptoms specifically in the longitudinal PATH survey, and found that never-smoking adults who used ECs at baseline had no increase in subsequent wheezing risk over a 5-year period in the US