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Acknowledgements Ethics declarations Competing interests The authors declare no competing interests

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Several clinical trials (including phase I, II, and III) for LHON gene therapy have been conducted (Table 2)

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Legal experts from the multinational law firm Han Kun identified three provisions that together create what they call a robust data exclusivity regime: protection for innovative drugs not yet approved globally, protection for drugs launched overseas but not yet approved in China, and related measures that close loopholes