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Oral or oropharyngeal cancer without HPV Stage 0 (Tis, N0, M0):The tumor is only in the surface layer of cells (carcinoma in situ) and hasn't spread to your lymph nodes or the rest of your body

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Principal coordinate analysis (PCoA) based on BrayCurtis inter-sample distance (PERMANOVA R 2 = 0.0413, p -value = 0.001) and unweighted UniFrac intersample distance (PERMANOVA, R 2 = 0.0454, p-value = 0.001) matrices showed clear separation between healthy and OSCC samples ( Figure 1C

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Jamal, M., Waheed, S., & Shakoor, A