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Accumulation of damaged mitochondria with swelling and cristae disruption in airway epithelial cells from COPD patients has been demonstrated [21, 22]

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Fermentation of different tobacco shapes by microorganisms TL fermentation: the screened microorganisms B1 and C4 were cultured at the logarithmic growth phase and centrifuged at 8000 rpm for 5 min to collect the cells and resuspended by adding the same volume of sterile water to obtain the bacterial suspension