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JAMA psychiatry, 2015

Prolonged exposure resulted in a change in OSCC morphology from polygonal to elongated, a decrease in the levels of the epithelial marker Cytokeratin-13 and an increase of mesenchymal markers (N-cadherin and -Smooth Muscle Acton (SMA)), indicating an Epithelial-to-Mesemchymal Transition (EMT) phenotype [121]