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The best way to quit smoking, Pechacek said, is by "accessing help" including free counseling over the phone via government "quitlines." In the United States, e-cigarettes are not approved or recommended as a smoking cessation aid, but two medications are: varenicline (Chantix) and the antidepressant bupropion (Wellbutrin)

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Cigarette smoke exposure also induced DNA-binding activity of nuclear factor kappaB (NFB) in osteoclasts, which subsequently gave rise to changes in bone remodeling-related gene expression