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32 (suppl 2)
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The ASD-related nosological entities are many, yet they all seem to reflect an abnormal development of the CNS in pre- and early postnatal periods, linked to either genetic heritage or environmental insults
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ROS act as secondary messengers to activate inflammasomes such as NLRP3, promoting the release of IL-1 and IL-18, and fostering the senescence-associated secretory phenotype (SASP)
It plays a role in chronic inflammation, a driver of long-term diabetic damage
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