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In cases of severe deficiency or pernicious anemia, injections may be given daily or weekly initially, followed by maintenance doses every month

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However, ROS accumulation after cellular redox imbalance could shift the balance toward oxidative stress, resulting in membrane and DNA damage, mutagenicity, tissue degeneration, apoptosis, and cancer [61]

331,332 In mesial temporal lobe epilepsy or tuberous sclerosis, astrocytes demonstrate a specific form of reactivity characterised by an increased expression of GFAP 333 and morphological atrophy manifested by reduced complexity of arbour and loss of distal leaflets

Surprisingly, our results suggest that GPX4 has dual functions in Raji cells: it inhibits cellular activity on the one hand and promotes EBV replication and proliferation on the other hand when GPX4 expression is inhibited