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Carnitine deficiency may contribute to a reduction in mitochondrial copy number and may disturb neurodevelopment, perhaps specifically affecting neurogenesis or synaptic development [75]

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These results suggest that radiation caused a lasting decline of antioxidant levels that may contribute to the pathogenesis of late effects

In addition, 8-oxo-Gs accumulate at telomeres, where they inhibit telomerase and decrease the binding of telomeric proteins, leading to the disruption of telomere length and precluding the maintenance of chromosomal-end capping 46