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Nat Rev Endocrinol (2016) 12:299308.10.1038/nrendo.2016.32 5 BarnesPJ

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The more nicotine you ingest, the higher the amount of cotinine in your urine

That group represents about 7,000 convenience stores throughout New England

Female nonsmokers showed higher BEN than male nonsmokers in prefrontal cortex, insula, and precuneus, but the BEN sex difference in smokers was less pronounced