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"Recently, the International Agency for Research on Cancer concluded that there is enough evidence to link paternal smoking in humans with increased risk of childhood cancer, suggesting that tobacco smoking causes heritable germ cell mutation in humans," wrote Francesco Marchetti of the Lawrence Berkeley National Laboratory in California, who led the new research, in a paper in the Proceedings of the National Academy of Sciences

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These acidic compounds are generated during the combustion and smoking processes, contributing to the pH balance of smoke, improving the mellowness of taste, and reducing irritation (Table 3