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"The substance's supposed benefits are largely based on anecdotal evidence, and the interest in it appears to be driven by those who stand to benefit from increased demand," Nina Zeldes, a researcher in Public Citizen's Health Research Group, told the committee

Available research consists primarily of laboratory and animal studies, with limited controlled human data

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Ondansetron for intravenous use: dose-dependent QT interval prolongation

A diagnosis of PA first requires demonstration of megaloblastic anemia by conducting a full blood count and blood smear, which evaluates the mean corpuscular volume (MCV), as well the mean corpuscular hemoglobin concentration (MCHC)

However, there are meaningful differences in how reliably these deliver B12 to the body compared with an injection