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In parallel, prenatal nicotine exposure results in epigenetic modifications in the testis and pituitary gland, including altered DNA methylation of genes involved in peripheral nervous system signaling such as those encoding transcription factors nuclear respiratory factor 1 and E26 transformation-specific variant 4, as well as -aminobutyric acid-related signaling components (19)

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Normally, your brain processes these and gives you that expected cigarette taste