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Barriers to implementation include concerns regarding drug interactions, increased costs, and adherence challenges due to regimen complexity

Not reliably

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In addition to assent provided by adolescent participants, informed consent was provided by their legal guardian

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Van Der Beek sometimes struggled to get out from under the shadow of the show but eventually leaned into lampooning himself, like on Funny Or Die videos and on Kesha's Blow music video, which included his laser gun battle with the pop star in a nightclub and dead unicorns