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Metabolism was terminated by adding acetonitrile, and the samples were analyzed by HPLC/MS

In another study, it was found that the essential oil of ZBE suppressed TNF-, IL-1, and IL-12 levels both in vivo and in vitro, as well as NLRP3 inflammasome activation in vivo [238]

This correlates with earlier discussions noting that the impact of dopamine on inflammation changes depending on the environment and suggests that dopamine mediated impairment in the inflammatory and antiviral response early in infection could predispose these animals to a more robust disease course (Emanuel et al., 2022)